Lyme disease is .. as they say .. overdiagnosed and underdiagnoed. I've certainly missed it. I've also ordered more Lyme antibody tests than I would like. In this region, Lyme disease is very common. This article – based on a study of data from Wisconsin – determines that Lyme testing is ordered far more frequently than necessary. I would agree. Yet the regional variation in the incidence of Lyme disease is significant. Your mileage may therefore vary.