Carvedilol Or Metoprolol European Trial (COMET)
If you really want to look smart, you know the cool name of the trial in addition to knowing what it means, and why it's important.
The COMET trial is important because it suggests that there may be something special about Carvedilol as compared to a generic beta blocker for the treatment of heart failure. Now .. is a 6% difference in outcomes worth the millions of dollars we'll spend on this medication rather than metoprolol or atenolol? Hmm